Mtundu wa anthu wamba wa anthu
Dzina lazogulitsa
HWTS-ge1 May Cyp2C19 Gellymorphism Wozindikira Kit (Fluorescence PCR)
Chiphaso
CE / tfda
Epidemiology
Cyp2C19 ndi imodzi mwazinthu zofunika kwambiri ma enzymes mu banja la Cyp450. Gawo lambiri la anthu awiri ndi 2% ya mankhwala azachipatala amapangidwa ndi cyp2c19, monga kagayini ya mankhwala osokoneza bongo (monga anticonvolel), anticonvoogrel, enc.19 mankhwala okhudzana. Izi zimasinthira kuti * 2 (RS424285) ndi * 3 (RS4986893) Jener Equation of the Cyyyme Kuzunzidwa kwa magazi. * 17 (rs12248560) imatha kuwonjezera ntchito ya enzyme yophatikizidwa ndi Gep2c19 Gene, ndikupanga ma metabolites, ndikuwonjezera chiopsezo chotchinga choletsa. Kwa anthu omwe ali ndi pang'onopang'ono kagayidwe ka mankhwala, kumwa mankhwala osokoneza bongo kwa nthawi yayitali kumayambitsa zovuta zazikulu komanso zoyipa: Kuwonongeka kwa chiwindi, kuwonongeka kwamitsempha yamanjenje, etc. Malinga ndi kusiyana komwe pakugwirizana ndi kagayidwe ka kagayidwe, nthawi zambiri imagawika mu ma phenotypes, kudziwikitsa kagayidwe kambiri (UM, * 17 / * 17, 1), 1 / * 1 ) * 3 / * 3).
Ngalande
| Banja | Cyp2c19 * 2 |
| Cy5 | Cyp2c9 * 3 |
| Rox | Cyp2c19 * 17 |
| Vic / Hex | IC |
Magawo aluso
| Kusunga | Madzi: ≤-18 ℃ |
| Alumali-Moyo | Miyezi 12 |
| Mtundu wofanana | Zatsopano edta anticoagated magazi |
| CV | ≤5.0% |
| Lodu | 1.0ng / μl |
| Chifanizo | Palibe mzere wokhazikika ndi mitundu ina yosasinthika (Cyp2C9 Gene) mu genome ya munthu. Masinthidwe a cyp2c19 * 23, cyp2c19 * 24 ndi cyp2c19 * Masamba 25 kunja kwa malowa alibe mphamvu pa zomwe zili mu Kit. |
| Zida Zogwirizira | Imagwiritsa ntchito ma biosyystems 7500 pcr PCR Systems Imagwiritsa ntchito bioshasystems 7500 mwachangu pcr pcr systems Ma pcr-5 a PCR Slan-96P yeniyeni PCR Systems Speccycler®480 PCR System Stonegene 9600 kuphatikiza njira zenizeni za PCR Ma-6000 enieni ochulukirapo Biorad Cfx96 PCR PCR System Biorad cfx opus 96 yeniyeni PCR |
Kuyenda
Kulimbikitsidwa Kutulutsa: Macro & Micro-Scro-Start DNA / RNA-3019) (yomwe ingagwiritsidwe ntchito ndi ma macro-eq011) Co., Ltd. Kuchotsa kuyenera kuchotsedwa molingana ndi malangizo. Buku la zitsanzo ndi 200μl, ndipo kuchuluka kwa Evest Evel ndi 100μL.
Kulimbikitsidwa Kutulutsa: Wizard® Gen Revielction Kit (cholembera ayi) ndi Promega, pulp348) ndi biijic. Iyenera kuchotsedwa malinga ndi malangizo a chiwombankhanga, ndi mawu olimbikitsidwa ndi 200 μl ndi mafakitale olimbikitsidwa ndi 160 μl.
