Khansa ya m'mapapo ikadali imodzi mwa zifukwa zazikulu padziko lonse zomwe zimayambitsa imfa zokhudzana ndi khansa, ndipokhansa ya m'mapapo yopanda maselo ang'onoang'ono (NSCLC)kuwerengera ndalama zoposa80%mwa milandu yonse ya khansa ya m'mapapo. Mu 2020 yokha, anthu oposa2.2 miliyoniMilandu yatsopano ya khansa ya m'mapapo yapezeka padziko lonse lapansi

Pamene njira yodziwira khansa ya m'magazi ikupitilira kusintha kayendetsedwe ka NSCLC,Kuyesa kusintha kwa EGFR kwakhala maziko a mankhwala olondola.Kuyambitsa kusintha kwa masinthidwe muCholandirira cha kukula kwa epidermal (EGFR)Majini ndi ena mwa ma biomarker omwe angathandize kwambiri pa matenda mu NSCLC, zomwe zimathandiza kusankha njira zochiritsira zomwe zimathandizira kwambiri zotsatira zachipatala mwa odwala oyenerera.

Poyerekeza ndi mankhwala ochiritsira a chemotherapy,EGFR tyrosine kinase inhibitors (TKIs)Kuletsa njira zosazolowereka zolumikizirana za EGFR zomwe zimayambitsa kukula ndi kupita patsogolo kwa chotupa, zomwe zimapangitsa kuti chikhale chogwira ntchito bwino komanso chitetezo chabwino kwa odwala omwe ali ndi EGFR-mutated NSCLC. Chifukwa chake, kuzindikira molondola komanso panthawi yake kwa kusintha kwa EGFR ndikofunikira kwambiri posankha chithandizo choyenera kwambiri komanso kuthandizira zisankho za chithandizo pambuyo pake pamene kukana kukukula.

Mfundo Zazikulu Zokhudza Malangizo

Malangizo otsogola azachipatala apadziko lonse lapansi nthawi zonse amagogomezera kufunika koyesa kwathunthu kwa biomarker mwa odwala omwe ali ndi NSCLC yapamwamba.

Malangizo a NCCN Clinical Practice mu Oncology

-Kulimbikitsa kuyesa kwathunthu kwa mamolekyulu musanayambe chithandizo choyamba mwa odwala omwe ali ndi NSCLC yapamwamba kapena yofalikira.

-Kusintha kwa EGFR ndikofunikira kwambiri posankha njira zoyenera zochiritsira.

ESMO Clinical Practice Guideline

Amalimbikitsa mayeso achizolowezi aKusintha kwa EGFR mu ma exons 18-21kuzindikira odwala oyenerera kulandira chithandizo chothandizidwa ndi EGFR.

Malangizo awa akuwonetsa ntchito yofunika kwambiri yoyesera kusintha kwa EGFR molondola, mosamala, komanso panthawi yake pothandiza odwala omwe ali ndi NSCLC kulandira chithandizo cholondola.

Kiti Yodziwira Kusintha kwa Ma EGFR Gene 29 ya Munthu (Fluorescence PCR)-Kuzindikira Molondola kwa Zisankho Zodalirika za Chithandizo

Mayeso a Macro ndi Micro-TestKiti Yodziwira Kusintha kwa Ma EGFR Gene 29 ya Munthu (Fluorescence PCR)zimathandiza kuzindikira mwachangu komanso molondola zaMasinthidwe 29 ofunika kwambiri a EGFR m'chipatalakudutsama exons 18–21, kuthandizira zisankho zolondola za chithandizo paulendo wonse wa wodwala.

Kuyesaku kumazindikira zonse ziwirikusintha kwa mankhwala komwe kumayambitsa kukana mankhwala komanso komwe kumagwirizana ndi kukana mankhwala, kuthandiza madokotala kuzindikira odwala omwe angapindule ndi mankhwala ochizira matenda a EGFR mongagefitinibndiosimertinib, pamene akuthandiza kupanga zisankho zochizira panthawi yonse ya chithandizo.

N’chifukwa Chiyani Muyenera Kusankha Chida Choyesera cha EGFR cha Macro & Micro-Test?

Kufotokozera Kwathunthu kwa Kusintha kwa Masinthidwe

• · KuzindikiraMasinthidwe 29 a EGFR okhudzana ndi matendakudutsa ma exons18–21
• · Zimaphimba zonse ziwirikuchititsa chidwi cha mankhwala osokoneza bongondizokhudzana ndi kukanakusintha kwa masinthidwe
• · Ukadaulo Wabwino wa ARMSyokhala ndi chowonjezera chokhala ndi patent kuti chikhale chowonjezera
• · Kukulitsa kwa Enzymaticamachepetsa mawonekedwe achilengedwe komanso amawongolera kulondola kwa kuzindikira
• · Ukadaulo Woletsa Kutenthaamachepetsa kukulitsa kosagwirizana ndipo amawonjezera kudziwika
• · Imazindikira kusintha kwa majini ndiMafupipafupi a allele osinthika a 1%
• · Zotsatira za cholinga mkati mwa mphindi 120
• · Kulamulira kwamkati ndiEnzyme ya UNGchepetsani zotsatira zabodza
• · Imathandizira zonse ziwiriminofu, plasma kapena seramuamples
• · Imagwirizana ndi zida za PCR zenizeni nthawi yeniyeni
• · Miyezi 12 yokhazikika

Ukadaulo Wodziwika Kwambiri

Kusanthula Kwambiri

Kayendedwe ka Ntchito Kosinthasintha

Chitsogozo cha Chithandizo ndi Chidaliro

Kuyesa kodalirika kwa kusintha kwa EGFR kumathandiza madokotala kupanga zisankho zolondola za chithandizo kuyambira poyambira kuzindikira matenda kudzera mu kuyang'anira kukana kwa matendawa.

Kuyesa kamodzi. Kuphunzira kwathunthu za kusintha kwa majini. Kudzidalira kwambiri popanga zisankho zachipatala.

Wonjezerani Precision Oncology Portfolio Yanu

Macro & Micro-Test imaperekanso mndandanda wathunthu wa mayankho odziwira mamolekyulu a khansa yolondola, kuphatikiza: KRAS, BRAF, ROS1, ALK, BCR-ABL, TEL-AML ndi zina zambiri…

Onani njira zathu zothetsera oncology:marketing@mmtest.com