Enterococcus yosamva Vancomycin ndi Gene yosamva Mankhwala

Kulimbana ndi Mankhwala kumatchedwanso kukana kwa mankhwala, kumatanthauza kukana kwa mabakiteriya kuti agwire ntchito ya antibacterial mankhwala.Kamodzi kukana mankhwala kumachitika, mphamvu ya chemotherapy ya mankhwala imachepetsedwa kwambiri.Resistance to Drug imagawidwa kukhala kukana kwachilengedwe komanso kupeza kukana.Kukaniza kwamkati kumatsimikiziridwa ndi majini a bakiteriya a chromosomal, omwe amadutsa ku mibadwomibadwo, ndipo sadzasintha.Kukaniza komwe kumapeza kumachitika chifukwa chakuti pambuyo pokhudzana ndi maantibayotiki, mabakiteriya amasintha njira zawo za metabolic kuti asaphedwe ndi maantibayotiki.

Vancomycin kukana majini VanA ndi VanB amapezedwa kukana mankhwala, amene VanA amasonyeza milingo mkulu kukana vancomycin ndi teicoplanin, VanB amasonyeza milingo yosiyanasiyana ya kukana vancomycin, ndi tcheru kwa teicoplanin.Vancomycin nthawi zambiri amagwiritsidwa ntchito kuchipatala pochiza matenda a bakiteriya a gram-positive, koma chifukwa cha kutuluka kwa vancomycin-resistant enterococci (VRE), makamaka enterococcus faecalis ndi enterococcus faecium, zomwe zimapitirira 90%, zabweretsa zovuta zazikulu pazachipatala. .Pakalipano, palibe mankhwala enieni a antibacterial ochizira VRE.Kuphatikiza apo, VRE imathanso kufalitsa majini osamva mankhwala ku enterococci kapena mabakiteriya ena a Gram-positive.