Kukana maantibayotiki (AMR) kwakhala chimodzi mwa ziwopsezo zazikulu kwambiri pa thanzi la anthu m'zaka za zana lino, zomwe zachititsa mwachindunji imfa zoposa 1.27 miliyoni chaka chilichonse komanso zomwe zapangitsa kuti anthu ena pafupifupi 5 miliyoni afe—vuto ladzidzidzi la thanzi lapadziko lonse lapansi likufunika kuti tichitepo kanthu mwachangu.
Sabata Yodziwitsa Anthu za AMR Padziko Lonse (Novembala 18-24), atsogoleri azaumoyo padziko lonse lapansi agwirizana kuti:"Chitanipo Kanthu Tsopano: Tetezani Zomwe Tili Nazo Panopa, Tetezani Tsogolo Lathu."Mutu uwu ukugogomezera kufunika kothana ndi vuto la AMR, lomwe limafuna khama logwirizana m'magawo onse a zaumoyo wa anthu, thanzi la nyama, ndi chilengedwe.
Chiwopsezo cha AMR chimadutsa malire a dziko ndi madera azaumoyo. Malinga ndi kafukufuku waposachedwa wa Lancet, popanda njira zogwirira ntchito zolimbana ndi AMR,Imfa zonse padziko lonse lapansi zitha kufika 39 miliyoni pofika chaka cha 2050, pomwe mtengo wapachaka wochiza matenda osamva mankhwala ukuyembekezeka kukwera kuchoka pa $66 biliyoni yomwe ilipo pano kufika paMadola 159 biliyoni.
Vuto la AMR: Zoona Zenizeni Zomwe Zili M'mbuyo mwa Manambala
Kukana mankhwala opha tizilombo toyambitsa matenda (AMR) kumachitika pamene tizilombo toyambitsa matenda—mabakiteriya, mavairasi, tizilombo toyambitsa matenda, ndi bowa—sitikuyankhanso mankhwala ochiritsira opha tizilombo toyambitsa matenda. Vuto la thanzi la padziko lonse lapansi lafika pamlingo woopsa:
-Mphindi 5 zilizonseMunthu m'modzi wamwalira chifukwa cha matenda osamva maantibayotiki
-Ndi2050, AMR ikhoza kuchepetsa GDP yapadziko lonse ndi 3.8%
-96% ya mayiko(onse 186) adatenga nawo gawo mu kafukufuku wapadziko lonse wa AMR wa 2024, zomwe zikusonyeza kuti anthu ambiri akuzindikira chiopsezochi.
-M'zipinda zosamalira odwala kwambiri m'madera ena,oposa 50% a mabakiteriya odzipatulakusonyeza kukana mankhwala opha tizilombo kamodzi kokha
Momwe Maantibayotiki Amalepherera: Njira Zodzitetezera za Tizilombo Tosaoneka ndi Maso
Maantibayotiki amagwira ntchito polimbana ndi mabakiteriya ofunikira:
-Kupanga Khoma la Maselo: Ma penicillin amasokoneza makoma a maselo a bakiteriya, zomwe zimapangitsa kuti mabakiteriya asweke komanso afe.
-Kupanga Mapuloteni: Tetracyclines ndi macrolides amaletsa ma ribosome a bakiteriya, ndikuletsa kupanga mapuloteni
-Kubwerezabwereza kwa DNA/RNAFluoroquinolones imaletsa ma enzyme ofunikira pakuberekana kwa DNA ya bakiteriya
-Kukhulupirika kwa Cell MembraneMa polymyxin amawononga nembanemba ya maselo a bakiteriya, zomwe zimapangitsa kuti maselo afe.
-Njira Zopangira Kagayidwe ka ThupiSulfonamides amaletsa njira zofunika kwambiri za mabakiteriya monga kupanga folic acid
Komabe, kudzera mu kusankha kwachilengedwe ndi kusintha kwa majini, mabakiteriya amapanga njira zingapo zopewera maantibayotiki, kuphatikizapo kupanga ma enzyme oletsa kugwira ntchito, kusintha zolinga za mankhwala, kuchepetsa kuchulukana kwa mankhwala, ndikupanga biofilms.
Carbapenemase: "Chida Chapamwamba Kwambiri" pa Vuto la AMR
Pakati pa njira zosiyanasiyana zotsutsira, kupangacarbapenemasesNdi nkhani yodetsa nkhawa kwambiri. Ma enzyme amenewa amathira ma hydrolyze ma antibiotic a carbapenem—omwe nthawi zambiri amaonedwa ngati mankhwala “omaliza”. Ma carbohydrate amagwira ntchito ngati “zida zamphamvu” za mabakiteriya, kuswa ma antibiotic asanalowe m'maselo a bakiteriya. Mabakiteriya omwe amanyamula ma enzyme amenewa—mongaKlebsiella chibayondiAcinetobacter baumannii—akhoza kupulumuka ndi kuchulukana ngakhale atagwiritsidwa ntchito ndi maantibayotiki amphamvu kwambiri.
Chodetsa nkhawa kwambiri n'chakuti, majini omwe amalemba ma carbapenema amapezeka pa majini oyenda omwe amatha kusamutsa mitundu yosiyanasiyana ya mabakiteriya,kufulumizitsa kufalikira kwa mabakiteriya osamva mankhwala ambiri padziko lonse lapansi.
Kuzindikira matendasMzere Woyamba wa Chitetezo mu Kulamulira kwa AMR
Kuzindikira molondola komanso mwachangu ndikofunikira kwambiri polimbana ndi AMR. Kuzindikira mabakiteriya osagonjetsedwa nthawi yake kungathe:
-Kupereka chithandizo choyenera, kupewa kugwiritsa ntchito mankhwala opha tizilombo molakwika
-Kukhazikitsa njira zowongolera matenda kuti tipewe kufalikira kwa mabakiteriya osagonjetsedwa
-Yang'anirani zomwe zikuchitika pa kukana kuti muthandize pa zisankho zaumoyo wa anthu onse
Mayankho Athu: Zida Zatsopano Zomenyera Nkhondo Molondola ya AMR
Pofuna kuthana ndi vuto la AMR lomwe likukula, Macro & Micro-Test yapanga zida zitatu zatsopano zopezera carbapenemase zomwe zikukwaniritsa zosowa zosiyanasiyana zachipatala, kuthandiza opereka chithandizo chamankhwala kuzindikira mabakiteriya omwe sagonjetsedwa mwachangu komanso molondola kuti atsimikizire kuti odwala alandira chithandizo choyenera komanso zotsatira zabwino.
1. Kiti Yodziwira Carbapenemase (Colloidal Gold)
Amagwiritsa ntchito ukadaulo wa colloidal gold kuti azindikire carbapenemase mwachangu komanso modalirika. Amagwiritsidwa ntchito m'zipatala, m'zipatala, komanso kunyumba, zomwe zimapangitsa kuti njira yodziwira matenda ikhale yosavuta komanso yolondola kwambiri.
Ubwino Waukulu:
-Kuzindikira Kwathunthu: Pa nthawi imodzi amazindikira majini asanu okana—NDM, KPC, OXA-48, IMP, ndi VIM
-Zotsatira Zachangu: Amapereka zotsatira mkati mwaMphindi 15, mofulumira kwambiri kuposa njira zachikhalidwe (masiku 1-2)
-Ntchito Yosavuta: Palibe zida zovuta kapena maphunziro apadera ofunikira, oyenera malo osiyanasiyana
-Kulondola Kwambiri: 95% kukhudzidwa popanda zotsatira zabodza kuchokera ku mabakiteriya wamba monga Klebsiella pneumoniae kapena Pseudomonas aeruginosa
2. Kiti Yodziwira Majini Okana ndi Carbapenem (Fluorescence PCR)
Yopangidwira kusanthula mozama majini a kukana kwa carbapenem. Yabwino kwambiri poyang'anira bwino m'ma laboratories azachipatala, popereka kuzindikira kolondola kwa majini angapo okana kwa carbapenem.
Ubwino Waukulu:
-Zitsanzo ZosinthasinthaKuzindikira mwachindunji kuchokeraMa colonies oyera, sputum, kapena rectal swabs—osakulitsachofunika
-Kuchepetsa Mtengo: Imazindikira majini asanu ndi limodzi ofunikira otsutsa (NDM, KPC, OXA-48, OXA-23) IMP, ndi VIM mu mayeso amodzi, kuchotsa mayeso owonjezera.
-Kuzindikira Kwambiri ndi Kudziwika BwinoMalire ozindikira ndi otsika ngati 1000 CFU/mL, palibe kuyanjana ndi majini ena otsutsa monga CTX, mecA, SME, SHV, ndi TEM.
-Kugwirizana Kwambiri: Imagwirizana ndiChitsanzo cha YankhoAIO 800 POCT yodziyimira yokha komanso zida zazikulu za PCR
3. Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa ndi Resistance Genes Multiplex Detection Kit (Fluorescence PCR)
Chida ichi chikuphatikiza kuzindikira mabakiteriya ndi njira zotsutsana ndi mabakiteriya mu njira imodzi yosavuta yodziwira matenda moyenera.
Ubwino Waukulu:
-Kuzindikira Kwathunthu: Amazindikira nthawi imodzimatenda atatu akuluakulu a bakiteriya—Klebsiella pneumoniae, Acinetobacter baumannii, ndi Pseudomonas aeruginosa—ndipo imapeza majini anayi ofunika kwambiri a carbapenemase (KPC, NDM, OXA48, ndi IMP) mu mayeso amodzi.
-Kuzindikira Kwambiri: Wokhoza kuzindikira DNA ya bakiteriya pamlingo wotsika mpaka 1000 CFU/mL
-Imathandizira Chisankho cha Zachipatala: Imathandiza kusankha mankhwala othandiza opha tizilombo toyambitsa matenda mwa kuzindikira msanga mitundu yolimbana ndi matendawa
-Kugwirizana Kwambiri: Imagwirizana ndiChitsanzo cha YankhoAIO 800 POCT yodziyimira yokha komanso zida zazikulu za PCR
Zipangizo zopezera matenda zimenezi zimapatsa akatswiri azaumoyo zida zothanirana ndi AMR pamlingo wosiyanasiyana—kuyambira kuyesa mwachangu mpaka kusanthula mwatsatanetsatane majini—kutsimikizira kuti chithandizo chachitika nthawi yake komanso kuchepetsa kufalikira kwa mabakiteriya osagonja.
Kulimbana ndi AMR ndi Precision Diagnostics
Ku Macro & Micro-Test, timapereka zida zamakono zodziwira matenda zomwe zimapatsa mphamvu opereka chithandizo chamankhwala chidziwitso chachangu komanso chodalirika, zomwe zimathandiza kusintha chithandizo panthawi yake komanso kuwongolera bwino matenda.
Monga momwe zanenedwera pa Sabata Yodziwitsa Anthu za AMR Padziko Lonse, zosankha zathu lero zidzatsimikizira kuthekera kwathu kuteteza mibadwo yamakono ndi yamtsogolo ku chiopsezo cha kusamva mankhwala ophera tizilombo toyambitsa matenda.
Lowani nawo nkhondo yolimbana ndi kukana maantibayotiki—moyo uliwonse wopulumutsidwa ndi wofunika.
For more information, please contact: marketing@mmtest.com
Nthawi yotumizira: Novembala-19-2025