Bowa Wofala, Choyambitsa Chachikulu cha Vaginitis ndi Matenda a Bowa a M'mapapo - Candida Albicans

Kufunika kwa Kuzindikira

Bowa wa candidiasis (womwe umadziwikanso kuti matenda a candida) ndi wofala kwambiri. Pali mitundu yambiri ya Candida ndimitundu yoposa 200 ya Candida akhalazomwe zapezeka mpaka pano.Candida albicans (CA) ndiye matenda oopsa kwambiri, zomwe zimawerengera pafupifupi 70% ya matenda onse opatsirana m'thupi.CA, yomwe imadziwikanso kuti Candida yoyera, nthawi zambiri imafalikira pakhungu la munthu, mkamwa, m'mimba, kumaliseche, ndi zina zotero. Ngati chitetezo cha mthupi cha munthu sichikugwira ntchito bwino kapena zomera zomwe zili bwino sizikuyenda bwino, CA mwina zimayambitsa matenda opatsirana m'thupi, matenda opatsirana m'mimba, matenda opatsirana m'mapapo, ndi zina zotero.

Matenda a nyini:Pafupifupi 75% ya akazi amadwala vulvovaginal candidiasis (VVC) kamodzi pa moyo wawo, ndipo theka la iwo amabwereranso. Kuwonjezera pa zizindikiro zopweteka zakuthupi monga kuyabwa ndi kutentha kwa vulvovaginal, milandu yoopsa ingayambitse kusakhazikika, komwe kumawonekera kwambiri usiku, komanso kumakhudza kwambiri malingaliro ndi maganizo a wodwalayo. VVC ilibe zizindikiro zenizeni zachipatala, ndipo mayeso a labotale ndiye chinsinsi chodziwira matendawa.

Matenda a fungal m'mapapo:CA matenda ndi chifukwa chachikulu cha imfa chifukwa cha matenda a m'chipatala ndipo zimafikira pafupifupi 40%odwala ambiri omwe ali mu ICU. Kafukufuku wofufuza matenda a bowa a m'mapapo ku China kuyambira 1998 mpaka 2007 adapeza kuti pulmonary candidiasis inali ndi 34.2%, ndipo mwa iwoCA 65% ya matenda a m'mapapo otchedwa pulmonary candidiasis.A Matendawa alibe zizindikiro za matenda wamba ndipo ali ndi zizindikiro zochepa zodziwika bwino pakuwonetsa, zomwe zimapangitsa kuti matenda oyamba ndi matenda a m'mapapo akhale ovuta. Akatswiri ogwirizana pankhani yozindikira ndi kuchiza matenda a bowa a m'mapapo amalimbikitsa kugwiritsa ntchito zitsanzo zoyenerera za sputum zomwe zafufuzidwa mozama, kulimbitsa mayeso a zamoyo, ndikupereka mapulani oyenera ochizira bowa.

Mitundu ya Zitsanzo

 

Yankho Lozindikira

Zinthu zomwe zili mu malonda

Kuchita bwino：Kukulitsa kwa Isothermal kuti kukwezedwe kosavuta ndi zotsatira mkati mwa mphindi 30;

Kufotokozera kwakukulu: Specific primer ndi probe (rProbe)zopangidwakwa madera otetezedwa kwambiri a CAyokhala ndi njira yotsekedwa bwino kuti izindikire makamaka DNA ya CA m'zitsanzo. Palibe kusinthana kwa majini ndi matenda ena opatsirana m'njira ya urogenital;

Kuzindikira kwambiri: LoD ya 10² mabakiteriya/mL;

QC Yogwira Ntchito: Kufotokozera kwamkati kwa reagent yowongolera ndi mtundu wa ntchito ndikupewa zoyipa zabodza;

Zotsatira zolondola: milandu 1,000 ya matenda opatsirana m'malo ambirir kuwunika kwachipatala ndi achiŵerengero chonse chotsata malamuloof 99.7%;

Kufalikira kwakukulu kwa ma serotypes: Ma serotypes onse a Candida albicans A, B, Czophimbidwa ndizotsatira zokhazikikapoyerekeza ndikuzindikira kutsatana;

Ma reagent otseguka: Amagwirizana ndi PCR yodziwika bwino yomwe ilipoma systma ems.

Zambiri Zamalonda

Khodi ya Zamalonda	Dzina la Chinthu	Kufotokozera	Nambala ya Chitsimikizo
HWTS-FG005	Nucleic Acid Detection Kit yochokera pa Enzymatic Probe Isothermal Amplification (EPIA) ya Candida Albicans	5Mayeso 0/zida
HWTS-EQ008	Amp YosavutaDongosolo Lozindikira Kutentha kwa Fluorescence nthawi yeniyeni	HWTS-1600P 4 njira zowala	NMPA2023322059
HWTS-EQ009		HWTS-1600s 2njira zowala