Chaka chilichonse pa Epulo 17 ndi Tsiku la Cancer Padziko Lonse.
01 Chidule cha Zochitika za Khansa Padziko Lonse
M'zaka zaposachedwapa, ndi kuwonjezeka kosalekeza kwa moyo wa anthu ndi kupsinjika maganizo, chiwerengero cha zotupa chikuwonjezekanso chaka ndi chaka.
Zotupa zowopsa (khansa) zakhala imodzi mwamavuto akulu azaumoyo omwe akuwopseza kwambiri thanzi la anthu aku China.Malinga ndi ziwerengero zaposachedwa, imfa ya zotupa zowopsa ndi 23,91% ya zomwe zimayambitsa imfa pakati pa anthu okhalamo, ndipo zochitika ndi kufa kwa zotupa zowopsa zapitilira kukwera zaka khumi zapitazi.Koma khansa sikutanthauza "chiweruzo cha imfa."Bungwe la World Health Organization linanena momveka bwino kuti malinga ngati atadziwika msanga, 60% -90% ya khansa imatha kuchiritsidwa!Gawo limodzi mwa magawo atatu a khansa imatha kupewedwa, gawo limodzi mwa magawo atatu a khansa ndi yochiritsika, ndipo gawo limodzi mwa magawo atatu a khansa amatha kuchiritsidwa kuti atalikitse moyo.
02 Chotupa ndi chiyani
Chotupa amatanthauza chamoyo chatsopano chopangidwa ndi kuchulukana m`deralo minofu maselo pansi zochita za zosiyanasiyana tumorigenic zinthu.Kafukufuku wapeza kuti maselo otupa amasintha kagayidwe kachakudya mosiyana ndi maselo abwinobwino.Nthawi yomweyo, maselo a chotupa amatha kusintha kusintha kwa kagayidwe kachakudya posinthana pakati pa glycolysis ndi oxidative phosphorylation.
03 Chithandizo cha Khansa Payekha
Chithandizo cha khansa yapayekha chimatengera chidziwitso cha majini omwe amayang'aniridwa ndi matenda komanso zotsatira za kafukufuku wamankhwala wozikidwa ndi umboni.Amapereka maziko kwa odwala kulandira ndondomeko yoyenera ya chithandizo, yomwe yakhala njira ya chitukuko chamankhwala chamakono.Kafukufuku wazachipatala watsimikizira kuti pozindikira kusintha kwa jini kwa ma biomarkers, kuyimira kwa jini ya SNP, jini ndi mawonekedwe ake a protein mu zitsanzo zamoyo za odwala chotupa kuti athe kuneneratu momwe mankhwalawo angagwiritsire ntchito bwino komanso kuwunika momwe amathandizira, ndikuwongolera chithandizo chamankhwala payekhapayekha, zitha kuwongolera bwino komanso kuchepetsa zovuta. zochita , kulimbikitsa kugwiritsa ntchito bwino mankhwala.
Kuyezetsa magazi kwa khansa kungagawidwe m'magulu atatu: matenda, cholowa, ndi chithandizo.Kuyeza kuchiza kumakhala pachimake cha zomwe zimatchedwa "mankhwala ochiritsira" kapena mankhwala opangidwa ndi makonda, ndipo ma antibodies ochulukirapo ndi zoletsa zazing'ono za mamolekyulu zomwe zimatha kulunjika kumtundu wamtundu wa chotupa ndi njira zozindikiritsira zitha kugwiritsidwa ntchito pochiza zotupa.
Thandizo la mamolekyulu la zotupa limalimbana ndi mamolekyu am'maselo a chotupa ndikulowererapo pama cell a khansa.Zotsatira zake zimakhala pa maselo otupa, koma zimakhala ndi zotsatira zochepa pa maselo abwinobwino.Chotupa kukula kwa zinthu zolandilira, ma siginecha transduction mamolekyu, ma cell cycle proteins, apoptosis regulators, proteinolytic enzymes, vascular endothelial growth factor, ndi zina zotere zitha kugwiritsidwa ntchito ngati ma cell chandamale cha chotupa.Pa Disembala 28, 2020, "Administrative Measures for the Clinical Application of Antineoplastic Drugs (Trial)" yoperekedwa ndi National Health and Medical Commission inanena momveka bwino kuti: Kwa mankhwala omwe ali ndi zolinga zomveka bwino za jini, mfundo yowagwiritsa ntchito iyenera kutsatiridwa pambuyo pake. kuyesa kwa jini.
04 Kuyesa kwa ma genetic kwa chotupa
Pali mitundu yambiri ya masinthidwe amtundu wa zotupa, ndipo mitundu yosiyanasiyana ya masinthidwe amtundu amagwiritsa ntchito mankhwala omwe amawatsata.Pokhapokha pofotokoza mtundu wa masinthidwe a jini ndikusankha moyenera mankhwala omwe akuwongolera omwe angapindule nawo.Njira zodziwira mamolekyulu zidagwiritsidwa ntchito kuti azindikire kusiyanasiyana kwa majini okhudzana ndi mankhwala omwe nthawi zambiri amakumana nawo m'matumbo.Powunika momwe ma genetic amakhudzira mphamvu ya mankhwala, titha kuthandiza madokotala kupanga njira yoyenera yamankhwala payekhapayekha.
05 Yankho
Macro & Micro-Test yapanga zida zingapo zodziwira majini a chotupa, zomwe zimapereka yankho lathunthu lamankhwala omwe amayang'aniridwa ndi chotupa.
Anthu EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR)
Chidachi chimagwiritsidwa ntchito pozindikira mu vitro moyenerera za masinthidwe wamba mu ma exons 18-21 a jini ya EGFR mu zitsanzo kuchokera kwa odwala omwe si ang'onoang'ono a khansa ya m'mapapo.
1. Dongosololi limayambitsa kuwongolera kwamtundu wamkati, komwe kumatha kuyang'anira mosamalitsa njira yoyesera ndikuwonetsetsa kuti kuyesako kuli bwino.
2. Kukhudzika kwakukulu: Kuzindikira kwa nucleic acid reaction solution kumatha kuzindikira mokhazikika kusintha kwa 1% pansi pa 3ng / μL mtundu wakuthengo.
3. Kukhazikika kwapamwamba: Palibe kuyanjana ndi DNA yamtundu wamunthu wamtchire ndi mitundu ina yosinthika.
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KRAS 8 Mutation Detection Kit (Fluorescence PCR)
Zidazi zimapangidwira kuti zizindikire zakusintha kwa 8 mu ma codon 12 ndi 13 a jini ya K-ras mu DNA yotengedwa m'magawo a paraffin ophatikizidwa ndi anthu.
1. Dongosololi limayambitsa kuwongolera kwamtundu wamkati, komwe kumatha kuyang'anira mosamalitsa njira yoyesera ndikuwonetsetsa kuti kuyesako kuli bwino.
2. Kukhudzika kwakukulu: Kuzindikira kwa nucleic acid reaction solution kumatha kuzindikira mokhazikika kusintha kwa 1% pansi pa 3ng / μL mtundu wakuthengo.
3. Kukhazikika kwapamwamba: Palibe kuyanjana ndi DNA yamtundu wamunthu wamtchire ndi mitundu ina yosinthika.
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Anthu EML4-ALK Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Chidachi chimagwiritsidwa ntchito pozindikira mitundu 12 yosinthika ya jini ya EML4-ALK mu zitsanzo za odwala omwe ali ndi khansa ya m'mapapo ya m'maselo.
1. Dongosololi limayambitsa kuwongolera kwamtundu wamkati, komwe kumatha kuyang'anira mosamalitsa njira yoyesera ndikuwonetsetsa kuti kuyesako kuli bwino.
2. Kukhudzika kwakukulu: Chida ichi chimatha kuzindikira masinthidwe ophatikizika otsika ngati makope a 20.
3. Kukhazikika kwapamwamba: Palibe kuyanjana ndi DNA yamtundu wamunthu wamtchire ndi mitundu ina yosinthika.
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Human ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Chidachi chimagwiritsidwa ntchito kuzindikira mu vitro qualitative kuzindikira kwa mitundu 14 ya masinthidwe amtundu wa ROS1 mu zitsanzo za khansa ya m'mapapo ya m'mapapo ya anthu.
1. Dongosololi limayambitsa kuwongolera kwamtundu wamkati, komwe kumatha kuyang'anira mosamalitsa njira yoyesera ndikuwonetsetsa kuti kuyesako kuli bwino.
2. Kukhudzika kwakukulu: Chida ichi chimatha kuzindikira masinthidwe ophatikizika otsika ngati makope a 20.
3. Kukhazikika kwapamwamba: Palibe kuyanjana ndi DNA yamtundu wamunthu wamtchire ndi mitundu ina yosinthika.
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Human BRAF Gene V600E Mutation Detection Kit (Fluorescence PCR)
Zida zoyeserazi zimagwiritsidwa ntchito kuti zizindikire kusintha kwa BRAF gene V600E mu zitsanzo zamtundu wa parafini wa melanoma yamunthu, khansa yapakhungu, khansa ya chithokomiro ndi khansa ya m'mapapo mu vitro.
1. Dongosololi limayambitsa kuwongolera kwamtundu wamkati, komwe kumatha kuyang'anira mosamalitsa njira yoyesera ndikuwonetsetsa kuti kuyesako kuli bwino.
2. Kukhudzika kwakukulu: Kuzindikira kwa nucleic acid reaction solution kumatha kuzindikira mokhazikika kusintha kwa 1% pansi pa 3ng / μL mtundu wakuthengo.
3. Kukhazikika kwapamwamba: Palibe kuyanjana ndi DNA yamtundu wamunthu wamtchire ndi mitundu ina yosinthika.
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| Nambala ya Catalog | Dzina lazogulitsa | Kufotokozera |
| HWTS-TM012A/B | Human EGFR Gene 29 Mutations Detection Kit (Fluorescence PCR) | 16 mayeso / zida, 32 mayeso / zida |
| HWTS-TM014A/B | KRAS 8 Mutation Detection Kit(Fluorescence PCR) | 24 mayeso / zida, 48 mayeso / zida |
| HWTS-TM006A/B | Anthu EML4-ALK Fusion Gene Mutation Detection Kit(Fluorescence PCR) | 20 mayeso / zida, 50 mayeso / zida |
| HWTS-TM009A/B | Human ROS1 Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 20 mayeso / zida, 50 mayeso / zida |
| HWTS-TM007A/B | Human BRAF Gene V600E Mutation Detection Kit(Fluorescence PCR) | 24 mayeso / zida, 48 mayeso / zida |
| Chithunzi cha HWTS-GE010A | Human BCR-ABL Fusion Gene Mutation Detection Kit (Fluorescence PCR) | 24 mayeso / zida |
Nthawi yotumiza: Apr-17-2023