Mycoabacterium chifuwa chachikulu nuclec acid ndi rifampicin kukana

Mycoabacterium chifuwarculosis, posachedwapa Bacille Bacillus, TB, ndi mankhwala a pathogenic omwe amayambitsa chifuwa chachikulu. Pakadali pano, kugwiritsa ntchito mankhwala oyamba ndi matenda a chifuwa . Komabe, chifukwa chogwiritsa ntchito molakwika Anti-chifuwa cha anti-chifuwa chachikulu ndi mawonekedwe a khoma la cellcrial chifuwa chachikulu cha mankhwala osokoneza bongo a anti-chifuwa chachikulu, chomwe chimabweretsa zovuta zazikulu zopewa komanso kuchiza matenda a chifuwa chachikulu.

Rifampicin agwiritsidwa ntchito kwambiri pochiza matenda a chifuwa chachikulu cha m'mapapo kuyambira kumapeto kwa m'ma 1970, ndipo ali ndi zotsatirapo zofunika. Yakhala chisankho choyamba kufupikitsa chemotherapy ya odwala chifuwa cha m'mapapo. Kukana kwa Rifampicin kumachitika chifukwa chosintha rpob gene. Ngakhale mankhwala atsopano a anti-chifuwa chachikulu amatuluka, ndipo thanzi la matenda a m'matumbo ambiri apitilizabe kusintha, pamakhala matenda a anti-chifuwa chachikulu, komanso chodabwitsa cha kugwiritsa ntchito mankhwala osokoneza bongo ndi okwera. Mwachidziwikire, mankhwala a Mycobacterium wa odwala omwe ali ndi chifuwa chachikulu amatha kuphedwa kwathunthu munthawi yake, omwe pamapeto pake amabweretsa digiri yosiyanasiyana ya wodwalayo, kutalikirana ndi matendawa, ndikuwonjezera chiopsezo cha imfa ya wodwalayo.