Mycoabacterium Tuberculosis rifampicin kukana

Rifampicin agwiritsidwa ntchito kwambiri pochiza matenda a chifuwa chachikulu cha m'mapapo kuyambira kumapeto kwa m'ma 1970, ndipo ali ndi zotsatirapo zofunika. Yakhala chisankho choyamba kufupikitsa chemotherapy ya odwala chifuwa cha m'mapapo. Kukana kwa Rifampicin kumachitika chifukwa chosintha rpob gene. Ngakhale mankhwala atsopano a anti-chifuwa chachikulu amatuluka, ndipo thanzi la matenda a m'matumbo ambiri apitilizabe kusintha, pamakhala matenda a anti-chifuwa chachikulu, komanso chodabwitsa cha kugwiritsa ntchito mankhwala osokoneza bongo ndi okwera. Mwachidziwikire, mankhwala a Mycobacterium wa odwala omwe ali ndi chifuwa chachikulu amatha kuphedwa kwathunthu munthawi yake, omwe pamapeto pake amabweretsa digiri yosiyanasiyana ya wodwalayo, kutalikirana ndi matendawa, ndikuwonjezera chiopsezo cha imfa ya wodwalayo. Izi zili zoyenera kuzindikiritsa matenda a mycobaclicin a matenda a rifampicin kukana matenda, omwe ndi othandiza kumvetsetsa kuchuluka kwa mankhwala a Mycobacterium percolis omwe ali ndi chitsogozo chamankhwala.