● Mycobacterium Tuberculosis
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Mycobacterium Tuberculosis Nucleic Acid ndi Rifampicin(RIF),Kukaniza(INH)
Chidachi chimagwiritsidwa ntchito pozindikira mu vitro qualitative ya Mycobacterium tuberculosis DNA mu sputum ya anthu, chikhalidwe cholimba (LJ Medium) ndi chikhalidwe chamadzimadzi (MGIT Medium), bronchial lavage fluid, ndi masinthidwe a 507-533 amino acid codon region (81bp, rifampicin resistance determining region of mycompicium tubercocci) komanso kusintha kwa masinthidwe a malo akuluakulu a Mycobacterium tuberculosis isoniazid resistance.Imathandiza kuzindikira matenda a chifuwa chachikulu cha Mycobacterium, ndipo imazindikira majini akuluakulu a rifampicin ndi isoniazid, omwe amathandiza kumvetsetsa kukana kwa mankhwala kwa Mycobacterium tuberculosis yomwe wodwala ali nayo.
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Mycobacterium Tuberculosis INH Mutation
Izi zida ndi oyenera kuzindikira Mkhalidwe wa zikuluzikulu masinthidwe malo mu anthu sputum zitsanzo zosonkhanitsidwa Tubercle bacillus HIV odwala amene amatsogolera mycobacterium TB INH: InhA kulimbikitsa dera -15C>T, -8T>A, -8T>C; Chigawo cholimbikitsa cha AhpC -12C>T, -6G>A; kusintha kwa homozygous kwa KatG 315 codon 315G>A, 315G>C.
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Mycobacterium Tuberculosis Rifampicin Resistance
Chidachi ndi choyenera kuzindikira zakusintha kwa homozygous m'chigawo cha 507-533 amino acid codon cha rpoB gene chomwe chimayambitsa Mycobacterium tuberculosis rifampicin resistance.
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Mycobacterium Tuberculosis Nucleic Acid ndi Rifampicin Resistance
Chidachi ndi choyenera kuzindikira za Mycobacterium tuberculosis DNA mu zitsanzo za sputum za anthu mu vitro, komanso kusintha kwa homozygous m'chigawo cha 507-533 amino acid codon cha jini ya rpoB yomwe imayambitsa kukana kwa Mycobacterium tuberculosis rifampicin.
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Mycobacterium Tuberculosis DNA
Ndi oyenera kuzindikira Mkhalidwe wa Mycobacterium chifuwa chachikulu DNA mu zitsanzo za anthu matenda sputum, ndipo ndi oyenera matenda wothandiza wa Mycobacterium chifuwa chachikulu matenda.
