MTHFR Gene Polymorphic Nucleic Acid
Dzina la malonda
HWTS-GE004-MTHFR Gene Polymorphic Nucleic Acid Detection Kit (ARMS-PCR)
Epidemiology
Folic acid ndi vitamini yosungunuka m'madzi yomwe ndi cofactor yofunikira m'njira za kagayidwe kachakudya m'thupi.M'zaka zaposachedwa, kafukufuku wambiri watsimikizira kuti, kusintha kwa jini ya folate metabolizing enzyme MTHFR kungayambitse kuchepa kwa folic acid m'thupi, komanso kuwonongeka kwa kusowa kwa folic acid mwa akulu kungayambitse megaloblastic anemia, mitsempha yamagazi. Kuwonongeka kwa endothelial, etc. Kuperewera kwa folic acid mwa amayi apakati sikungathe kukwaniritsa zosowa zawo ndi mwana wosabadwayo, zomwe zingayambitse neural chubu zolakwika, anencephaly, kubereka, ndi kupititsa padera.Miyezo ya serum folate imakhudzidwa ndi ma polymorphisms a 5,10-methylenetetrahydrofolate reductase (MTHFR).Kusintha kwa 677C>T ndi 1298A>C mu jini ya MTHFR kumapangitsa kusintha kwa alanine kukhala valine ndi glutamic acid, motero, zomwe zimapangitsa kuti ntchito ya MTHFR ichepe ndipo chifukwa chake kuchepetsa kugwiritsidwa ntchito kwa folic acid.
Channel
| FAM | Mtengo wa MTHFR C677T |
| Mtengo ROX | MTHFR A1298C |
| VIC (HEX) | Ulamuliro wamkati |
Magawo aukadaulo
| Kusungirako | ≤-18 ℃ |
| Alumali moyo | 12 miyezi |
| Mtundu wa Chitsanzo | Magazi a anticoagulated a EDTA osonkhanitsidwa kumene |
| CV | ≤5.0% |
| Ct | ≤38 |
| LoD | 1.0ng/μL |
| Zida Zomwe Zingagwiritsidwe Ntchito: | Applied Biosystems 7500 Real-Time PCR Systems Applied Biosystems 7500 Fast Real-Time PCR Systems SLAN ®-96P Real-Time PCR Systems QuantStudio™ 5 Real-Time PCR Systems LightCycler®480 Real-Time PCR system LineGene 9600 Plus Real-Time PCR Detection System MA-6000 Real-Time Quantitative Thermal Cycler BioRad CFX96 Real-Time PCR System BioRad CFX Opus 96 Real-Time PCR System |
Kuyenda Ntchito
Njira 1
Zopangira zopangira zovomerezeka: Macro & Micro-Test Genomic DNA Kit (HWTS-3014-32, HWTS-3014-48, HWTS-3014-96) ndi Macro & Micro-Test Automatic Nucleic Acid Extractor(HWTS-3006C, HWTS-300) .
Njira 2
Zopangira zopangira zovomerezeka: Magazi a Genomic DNA Extraction Kit(YDP348, JCXB20210062) lolemba Tiangen Biotech(Beijing) Co.,Ltd.Magazi a Genome Extraction Kit(A1120) wolemba Promega.
