Alpha Fetoprotein(AFP) Kuchuluka

Alpha-fetoprotein (alpha fetoprotein, AFP) ndi glycoprotein yokhala ndi molekyulu yolemera pafupifupi 72KD yopangidwa ndi yolk sac ndi ma cell a chiwindi kumayambiriro kwa chitukuko cha embryonic.Imachulukirachulukira m'magazi a mwana wosabadwayo, ndipo kuchuluka kwake kumatsika pakatha chaka chimodzi chibadwire.Mlingo wamagazi wamunthu wamkulu umakhala wotsika kwambiri.Zomwe zili mu AFP zimagwirizana ndi kuchuluka kwa kutupa ndi necrosis ya maselo a chiwindi.Kukwera kwa AFP ndikuwonetsa kuwonongeka kwa maselo a chiwindi, necrosis, ndi kuchulukana kotsatira.Kuzindikira kwa alpha-fetoprotein ndichizindikiro chofunikira pakuwunika kwachipatala komanso kuwunika kwa khansa yachiwindi.Zakhala zikugwiritsidwa ntchito kwambiri pozindikira chotupa muzachipatala.

Kutsimikiza kwa alpha-fetoprotein kungagwiritsidwe ntchito pochiza matenda, kuchiritsa komanso kuzindikira za khansa yayikulu ya chiwindi.M'matenda ena (khansa ya testicular non-seminoma, neonatal hyperbilirubinemia, pachimake kapena matenda a virus a hepatitis, cirrhosis yachiwindi ndi matenda ena owopsa), kuwonjezeka kwa alpha-fetoprotein kumatha kuwoneka, ndipo AFP sayenera kugwiritsidwa ntchito ngati kuyezetsa kansa. chida.