● Oncology
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Anthu TEL-AML1 Fusion Gene Mutation
Zidazi zimagwiritsidwa ntchito pozindikira zamtundu wa TEL-AML1 fusion jini m'mafupa amunthu mu vitro.
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Human Methylated NDRG4/SEPT9/SFRP2/BMP3/SDC2 Gene
Chidacho chimapangidwira kuti chizindikiridwe chamtundu wa methylated NDRG4/SEPT9/SFRP2/BMP3/SDC2 m'maselo otuluka m'matumbo amtundu wa anthu.
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Munthu BRAF Gene V600E Kusintha
Zida zoyeserazi zimagwiritsidwa ntchito kuti zizindikire kusintha kwa BRAF gene V600E mu zitsanzo zamtundu wa parafini wa melanoma yamunthu, khansa yapakhungu, khansa ya chithokomiro ndi khansa ya m'mapapo mu vitro.
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Munthu BCR-ABL Fusion Gene Mutation
Zidazi ndizoyenera kuzindikira za p190, p210 ndi p230 isoforms za jini yophatikizika ya BCR-ABL mu zitsanzo za m'mafupa aumunthu.
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Kusintha kwa KRAS 8
Zidazi zimapangidwira kuti zizindikire zakusintha kwa 8 mu ma codon 12 ndi 13 a jini ya K-ras mu DNA yotengedwa m'magawo a paraffin ophatikizidwa ndi anthu.
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Anthu EGFR Gene 29 Mutations
Chidachi chimagwiritsidwa ntchito pozindikira mu vitro moyenerera za masinthidwe wamba mu ma exons 18-21 a jini ya EGFR mu zitsanzo kuchokera kwa odwala omwe si ang'onoang'ono a khansa ya m'mapapo.
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Munthu ROS1 Fusion Gene Mutation
Chidachi chimagwiritsidwa ntchito pozindikira mu vitro qualitative qualitative ya mitundu 14 ya masinthidwe amtundu wa ROS1 fusion mu zitsanzo za khansa ya m'mapapo yamunthu yomwe si yaying'ono (Table 1).Zotsatira zoyezetsa ndizongofotokozera zachipatala zokha ndipo siziyenera kugwiritsidwa ntchito ngati njira yokhayo yothandizira odwala payekhapayekha.
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Anthu EML4-ALK Fusion Gene Mutation
Chidachi chimagwiritsidwa ntchito pozindikira mitundu 12 yosinthika ya jini ya EML4-ALK mu zitsanzo za odwala omwe ali ndi khansa ya m'mapapo ya m'maselo.Zotsatira zoyezetsa ndizongofotokozera zachipatala zokha ndipo siziyenera kugwiritsidwa ntchito ngati njira yokhayo yothandizira odwala payekhapayekha.Madokotala akuyenera kuweruza mwatsatanetsatane zotsatira za kuyezetsa kutengera zinthu monga momwe wodwalayo alili, zizindikiro za mankhwala, kuyankhidwa kwamankhwala, ndi zizindikiro zina za labotale.
