Mankhwala a Monkeypox Virus IgM/IgG Antibody

Monkeypox (MPX) ndi matenda opatsirana a zoonotic omwe amayamba chifukwa cha Monkeypox Virus (MPXV). MPXV ndi kachilombo ka DNA kamene kali ndi mikwingwirima iwiri kokhala ndi njerwa yozungulira kapena yozungulira ndipo ndi kutalika kwa pafupifupi 197Kb. Matendawa amafalikira makamaka ndi nyama, ndipo anthu amatha kutenga matendawa polumidwa ndi nyama zomwe zili ndi matendawa kapena pokhudzana mwachindunji ndi magazi, madzi amthupi ndi ziphuphu za nyama zomwe zili ndi matendawa. Kachiromboka kamathanso kufalikira kuchokera kwa munthu kupita kwa munthu, makamaka kudzera m'madontho a mpweya panthawi yolumikizana maso ndi maso kwa nthawi yayitali kapena kudzera mu kukhudzana mwachindunji ndi madzi amthupi kapena zinthu zodetsedwa za odwala. Zizindikiro zachipatala za matenda a monkeypox mwa anthu ndizofanana ndi za nthomba, ndi malungo, mutu, kupweteka kwa minofu ndi msana, kutupa kwa lymph nodes, kutopa komanso kusasangalala pambuyo pa masiku 12 obadwa. Ziphuphu zimawonekera patatha masiku 1-3 kuchokera pamene malungo achitika, nthawi zambiri pankhope, komanso m'malo ena. Matendawa nthawi zambiri amatenga milungu 2-4, ndipo chiwerengero cha imfa ndi 1%-10%. Lymphadenopathy ndi chimodzi mwa kusiyana kwakukulu pakati pa matendawa ndi nthomba.

Kiti iyi imatha kuzindikira ma antibodies a kachilombo ka monkey pox IgM ndi IgG mu chitsanzo nthawi imodzi. Zotsatira zabwino za IgM zimasonyeza kuti munthuyo ali mu nthawi yodwala, ndipo zotsatira zabwino za IgG zimasonyeza kuti munthuyo adadwala kale kapena ali mu nthawi yochira matenda.