Nyuni yaumunthu ya Umunthu ROS1
Dzina lazogulitsa
HWTS-TM009-Has-Has1 ros1 ku Get Ruaction Renation Kit (Fluorescence PCR)
Chiphaso
CE
Epidemiology
Ros1 ndi transmerane tyrosine kinase wa banja lolandirira insulin. ROS1 NKHANIYI imatsimikiziridwa ngati ina yofunika yosadziwika ya cell. Monga woimira subype yatsopano, matenda a ros1 a ros1 jini mu 1% mpaka 2% ros1 makamaka ros1 makamaka majini amasinthanso ndi majini monga CD74, EZR, SLC34A2, ndi SDC4, ipitiliza kuyambitsa dera la Rosine Kinase. KINARRORDARD APTION ROS1 Kinase imatha kuyambitsa njira zotsika kwambiri monga RAS / Mapk / Thk, ndi Jakt / Ak3 / Akt Pakati pa ros1 mokakamizidwa, CD74-ROS1 za 42%, EZR 2%, SCC34a2 ya 12%, ndi sdc4 pa 7%. Kafukufuku wawonetsa kuti tsamba la matp-kinase la ros1 kinase ndi malo omanga a Alk ali ndi bology ya ma 77% Mankhwalawa nsclc ndi zonunkhira mosinthana ndi Ros1. Chifukwa chake, kuzindikira za Ros1 kusinthira masinthidwe ndi maziko otsogolera kugwiritsa ntchito mankhwala osokoneza bongo.
Ngalande
| Banja | Kuchita Buffer 1, 2, 3 ndi 4 |
| Vic (Hex) | Mphepo yonyamula 4 |
Magawo aluso
| Kusunga | ≤-18 ℃ |
| Alumali-Moyo | Miyezi 9 |
| Mtundu wofanana | Paraffin-Matumbo Ophatikizidwa ndi Minofu ya Parail kapena zitsanzo |
| CV | <5.0% |
| Ct | ≤38 |
| Lodu | Izi zitha kuzindikira manyazi otsika ngati makope 20. |
| Zida Zogwirizira: | Imagwiritsa ntchito ma biosyystems 7500 pcr PCR SystemsImagwiritsa ntchito bioshasystems 7500 mwachangu pcr pcr systems Slan ®-96p PCR Systems Ma pcrudidio ™ 5 Speccycler®480 PCR System Stonegene 9600 kuphatikiza njira zenizeni za PCR Ma-6000 enieni ochulukirapo Biorad Cfx96 PCR PCR System Biorad cfx opus 96 yeniyeni PCR |
Kuyenda
Cholinga cholimbikitsidwa: Rneasy FFPE Kit (73504) kuchokera ku Qagen gawo la mitu yodzaza ndi RNA Kutulutsa Kiang (DP439) kuchokera ku TIAngEN Biotech (Beijing), LTD.
