Mtundu wa anthu bcr-abl
Dzina lazogulitsa
HWTS-ge10a-Happ-Habr-Abl Zima ku Celi Vent Berland (Fluorescence PCR)
HWTS-ge016a-Free-Flezeted Abl Mage Abl Movie Gene Wosagwirizana Nat Kit (Fluorescence PCR)
Epidemiology
Matenda a myelogenousleukemia (cml) ndi matenda owopsa a hematopoietic tsinde. Oposa 95% ya odwala cml amakhala ndi Philadelphia chromosome (pH) m'maselo awo amwazi. Nthaka yayikulu ya cml ndi motere: REL-ABL Purce imapangidwa ndi kuyika pakati pa Abl promosome (9Q34) ndi malo osokoneza bongo ( BCR) Gene pa mkono wautali wa chromosome 22 (22Q11); Ma protein ophatikizidwa ndi Run uyu ali ndi tyrosine kinase (TK) ntchito, ndikupangitsa masentimita, ndikupanga maselo owoneka bwino, ndipo potero amayambitsa kupezeka kwa cml. BCR-ABL ndi imodzi mwazizindikiro zofunika kuzimvetsetsa za cml. Kusintha kwamphamvu kwa kalembedwe kake ndi chizindikiro chodalirika kuti chitsimikiziro cha leukemia ndipo chitha kugwiritsidwa ntchito kulosera za leukemia pambuyo chithandizo.
Ngalande
| Banja | BCR-ABL Fing Gen |
| Vic / Hex | Kuwongolera kwamkati |
Magawo aluso
| Kusunga | Madzi: ≤-18 ℃ mdima |
| Alumali-Moyo | Madzi: miyezi 9 |
| Mtundu wofanana | Zitsanzo za Mafupa |
| Lodu | 1000 makope / ml |
| Chifanizo
| Palibe Mphepo Yapakatikati Ndi NKHANI YOSAVUTA AME-Aml1, E2a-PBX1, Mll-Af4, Aml1-ETO, ndi PMLA |
| Zida Zogwirizira | Imagwiritsa ntchito ma biosyystems 7500 pcr PCR Systems Imagwiritsa ntchito bioshasystems 7500 mwachangu pcr pcr systems Ma pcr apamwamba Slan-96P yeniyeni PCR Systems Speccycler®480 PCR System Stonegene 9600 kuphatikiza njira zenizeni za PCR Ma-6000 enieni ochulukirapo Biorad Cfx96 PCR PCR System Biorad cfx opus 96 yeniyeni PCR |
