Dengue NS1 Antigen, IgM/IgG Antibody Dual

Matenda a Dengue ndi matenda opatsirana omwe amayamba chifukwa cha kulumidwa ndi udzudzu wachikazi womwe uli ndi kachilombo ka dengue (DENV), komwe kamafalikira mofulumira, kufalikira kwambiri, kufalikira kwa matendawa, komanso kufa kwambiri pazochitika zoopsa.^.

Anthu pafupifupi 390 miliyoni padziko lonse lapansi amadwala matenda a dengue fever chaka chilichonse, ndipo anthu 96 miliyoni amakhudzidwa ndi matendawa m'maiko opitilira 120, makamaka ku Africa, America, Southeast Asia ndi Western Pacific. Pamene kutentha kwa dziko kukuchulukirachulukira, matenda a dengue fever akufalikira kumadera otentha komanso ozizira komanso m'malo okwera kwambiri, ndipo kufalikira kwa matenda a serotypes kukusintha. M'zaka zaposachedwapa, mliri wa matenda a dengue fever uli woopsa kwambiri ku South Pacific, Africa, South America, kum'mwera kwa Asia ndi Southeast Asia, ndipo ukuwonetsa kuchuluka kosiyanasiyana kwa matenda opatsirana a serotype, malo okwera, nyengo, kuchuluka kwa imfa ndi chiwerengero cha matenda.

Deta yovomerezeka ya WHO mu Ogasiti 2019 inasonyeza kuti panali milandu pafupifupi 200,000 ya malungo a dengue ndi imfa 958 ku Philippines. Malaysia inali itasonkhanitsa milandu yoposa 85,000 ya dengue pakati pa Ogasiti 2019, pomwe Vietnam inali itasonkhanitsa milandu 88,000. Poyerekeza ndi nthawi yomweyi mu 2018, chiwerengerochi chinakwera kuwirikiza kawiri m'maiko onse awiri. WHO yaona malungo a dengue ngati vuto lalikulu paumoyo wa anthu.

Chogulitsachi ndi chida chodziwira matenda a dengue NS1 antigen ndi IgM/IgG antibody mwachangu, pamalopo komanso molondola. Antibody yeniyeni ya IgM imasonyeza kuti pali kachilombo kamene kachitika posachedwapa, koma mayeso a IgM olakwika satsimikizira kuti thupi silinatenge kachilomboka. Ndikofunikiranso kuzindikira ma antibodies enaake a IgG okhala ndi theka la moyo wautali komanso kuchuluka kwambiri kuti atsimikizire matendawa. Kuphatikiza apo, thupi likatenga kachilomboka, antigen ya NS1 imawonekera koyamba, kotero kuzindikira nthawi yomweyo kwa antigen ya dengue NS1 antigen ndi ma antibodies enaake a IgM ndi IgG kumatha kuzindikira bwino momwe chitetezo cha mthupi chimayankhira ku kachilombo kena, ndipo chida chodziwira matenda a antigen-antibody ichi chimatha kuzindikira msanga komanso kuyesa msanga pachiyambi cha matenda a dengue, matenda oyamba ndi matenda achiwiri kapena angapo a dengue, kufupikitsa nthawi yowonekera ndikuwonjezera kuchuluka kwa matendawa.