Dengue NS1 Antigen, IgM/IgG Antibody Dual

Dengue fever ndi matenda opatsirana omwe amayamba chifukwa cha kulumidwa ndi udzudzu waukazi womwe umanyamula kachilombo ka dengue (DENV), womwe umafala mwachangu, umapezeka kwambiri, umakhala wovuta kwambiri, komanso umafa kwambiri nthawi zambiri.^.

Pafupifupi anthu 390 miliyoni padziko lonse lapansi amadwala matenda a dengue fever chaka chilichonse, ndipo anthu 96 miliyoni amakhudzidwa ndi matendawa m'mayiko oposa 120, omwe ali ovuta kwambiri ku Africa, America, Southeast Asia ndi Western Pacific.Pamene kutentha kwa dziko kukuchulukirachulukira, matenda a dengue tsopano akufalikira kumadera ozizira ndi ozizira komanso okwera, ndipo kufalikira kwa serotypes kukusintha.M'zaka zaposachedwa, mliri wa matenda a dengue fever ndi wovuta kwambiri kudera la South Pacific, Africa, South America, kum'mwera kwa Asia ndi Southeast Asia, ndipo ukuwonetsa magawo osiyanasiyana akuwonjezeka kwamtundu wa serotype, malo okwera, nyengo, kuchuluka kwa anthu omwe amafa komanso kuchuluka kwa matenda.

Zambiri za WHO mu Ogasiti 2019 zidawonetsa kuti panali anthu pafupifupi 200,000 a matenda a dengue fever ndi 958 afa ku Philippines.Malaysia idapeza anthu opitilira 85,000 a dengue mkati mwa Ogasiti 2019, pomwe Vietnam idapeza milandu 88,000.Poyerekeza ndi nthawi yomweyi mu 2018, chiwerengerochi chinawonjezeka kuwirikiza kawiri m'mayiko onsewa.WHO yaona matenda a dengue monga vuto lalikulu la thanzi la anthu.

Chogulitsachi ndi chachangu, chapamalo komanso chodziwira molondola kachilombo ka dengue NS1 antigen ndi IgM/IgG.Ma antibody enieni a IgM akuwonetsa kuti pali matenda aposachedwa, koma kuyesa kwa IgM sikutsimikizira kuti thupi silinadwale.Ndikofunikiranso kuzindikira ma antibodies enieni a IgG okhala ndi theka la moyo wautali komanso zomwe zili pamwamba kwambiri kuti zitsimikizire za matendawa.Kuphatikiza apo, thupi likadwala, antigen ya NS1 imawonekera koyamba, kotero kuti kuzindikirika kwa kachilombo ka dengue NS1 antigen ndi ma antibodies enieni a IgM ndi IgG kumatha kuzindikira bwino momwe chitetezo cha mthupi chimayankhira ku tizilombo toyambitsa matenda, ndipo antigen-antibody iyi imaphatikizana. Chidacho chimatha kuzindikira msanga msanga ndikuwunika matenda a dengue, matenda oyamba ndi matenda a dengue achiwiri kapena angapo, kufupikitsa nthawi yazenera ndikuwongolera kuchuluka kwa anthu.